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Alginic Acid-Coated Chitosan Nanoparticles Loaded with Legumain DNA Vaccine: Effect against Breast Cancer in Mice

Legumain-based DNA vaccines have potential to protect against breast cancer. However, the lack of a safe and efficient oral delivery system restricts its clinical application. Here, we constructed alginic acid-coated chitosan nanoparticles (A.C.NPs) as an oral delivery carrier for a legumain DNA vac...

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Detalles Bibliográficos
Autores principales: Liu, Ze, Lv, Dan, Liu, Shu, Gong, Junbo, Wang, Da, Xiong, Min, Chen, Xiaoniao, Xiang, Rong, Tan, Xiaoyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618226/
https://www.ncbi.nlm.nih.gov/pubmed/23577091
http://dx.doi.org/10.1371/journal.pone.0060190