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Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop

BACKGROUND: Pancreatic cancer shows a highly aggressive and infiltrative growth pattern and is characterized by an abundant tumor stroma known to interact with the cancer cells, and to influence tumor growth and drug resistance. Cancer cells actively take part in the production of extracellular matr...

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Detalles Bibliográficos
Autores principales: Öhlund, Daniel, Franklin, Oskar, Lundberg, Erik, Lundin, Christina, Sund, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618250/
https://www.ncbi.nlm.nih.gov/pubmed/23530721
http://dx.doi.org/10.1186/1471-2407-13-154