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Derepression of Cancer/Testis Antigens in cancer is associated with distinct patterns of DNA Hypomethylation

BACKGROUND: The Cancer/Testis Antigens (CTAs) are a heterogeneous group of proteins whose expression is typically restricted to the testis. However, they are aberrantly expressed in most cancers that have been examined to date. Broadly speaking, the CTAs can be divided into two groups: the CTX antig...

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Detalles Bibliográficos
Autores principales: Kim, Robert, Kulkarni, Prakash, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618251/
https://www.ncbi.nlm.nih.gov/pubmed/23522060
http://dx.doi.org/10.1186/1471-2407-13-144