Enzyme inhibition of dopamine metabolism alters 6-[(18)F]FDOPA uptake in orthotopic pancreatic adenocarcinoma

BACKGROUND: An unknown location hampers removal of pancreatic tumours. We studied the effects of enzyme inhibitors on the uptake of 6-[(18)F]fluoro-l-3,4-dihydroxyphenylalanine ([(18)F]FDOPA) in the pancreas, aiming at improved imaging of pancreatic adenocarcinoma. METHODS: Mice bearing orthotopic B...

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Detalles Bibliográficos
Autores principales: Tuomela, Johanna, Forsback, Sarita, Haavisto, Laura, Vahlberg, Tero, Grönroos, Tove J, Solin, Olof, Haaparanta-Solin, Merja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618317/
https://www.ncbi.nlm.nih.gov/pubmed/23497589
http://dx.doi.org/10.1186/2191-219X-3-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618317/
https://www.ncbi.nlm.nih.gov/pubmed/23497589
http://dx.doi.org/10.1186/2191-219X-3-18

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