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Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis

BACKGROUND: The neuroinflammatory response aimed at clearance of herpes simplex virus-1 (HSV-1) plays a key role in the pathogenesis of neuroaxonal damage in herpetic encephalitis. Leukocytes activated in an adaptive immune response access brain tissue by passing through the blood–brain barrier. The...

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Detalles Bibliográficos
Autores principales: Vilela, Márcia Carvalho, Lima, Graciela Kunrath, Rodrigues, David Henrique, Lacerda-Queiroz, Norinne, Pedroso, Vinicius Sousa Pietra, Miranda, Aline Silva, Rachid, Milene Alvarenga, Kroon, Erna Geessien, Campos, Marco Antônio, Teixeira, Mauro Martins, Sellner, Johann, Teixeira, Antonio Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618319/
https://www.ncbi.nlm.nih.gov/pubmed/23391218
http://dx.doi.org/10.1186/1471-2202-14-19