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Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis
BACKGROUND: The neuroinflammatory response aimed at clearance of herpes simplex virus-1 (HSV-1) plays a key role in the pathogenesis of neuroaxonal damage in herpetic encephalitis. Leukocytes activated in an adaptive immune response access brain tissue by passing through the blood–brain barrier. The...
Autores principales: | Vilela, Márcia Carvalho, Lima, Graciela Kunrath, Rodrigues, David Henrique, Lacerda-Queiroz, Norinne, Pedroso, Vinicius Sousa Pietra, Miranda, Aline Silva, Rachid, Milene Alvarenga, Kroon, Erna Geessien, Campos, Marco Antônio, Teixeira, Mauro Martins, Sellner, Johann, Teixeira, Antonio Lucio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618319/ https://www.ncbi.nlm.nih.gov/pubmed/23391218 http://dx.doi.org/10.1186/1471-2202-14-19 |
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