Donor DNA Utilization During Gene Targeting with Zinc-Finger Nucleases

Gene targeting is the term commonly applied to experimental gene replacement by homologous recombination (HR). This process is substantially stimulated by a double-strand break (DSB) in the genomic target. Zinc-finger nucleases (ZFNs) are targetable cleavage reagents that provide an effective means...

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Detalles Bibliográficos
Autores principales: Beumer, Kelly J., Trautman, Jonathan K., Mukherjee, Kusumika, Carroll, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618352/
https://www.ncbi.nlm.nih.gov/pubmed/23550125
http://dx.doi.org/10.1534/g3.112.005439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618352/
https://www.ncbi.nlm.nih.gov/pubmed/23550125
http://dx.doi.org/10.1534/g3.112.005439

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