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Donor DNA Utilization During Gene Targeting with Zinc-Finger Nucleases

Gene targeting is the term commonly applied to experimental gene replacement by homologous recombination (HR). This process is substantially stimulated by a double-strand break (DSB) in the genomic target. Zinc-finger nucleases (ZFNs) are targetable cleavage reagents that provide an effective means...

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Detalles Bibliográficos
Autores principales:	Beumer, Kelly J., Trautman, Jonathan K., Mukherjee, Kusumika, Carroll, Dana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2013
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618352/ https://www.ncbi.nlm.nih.gov/pubmed/23550125 http://dx.doi.org/10.1534/g3.112.005439

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