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Transcriptome Profiling Following Neuronal and Glial Expression of ALS-Linked SOD1 in Drosophila

Amyotrophic lateral sclerosis (ALS) generally is a late-onset neurodegenerative disease. Mutations in the Cu/Zn superoxide dismutase 1 (SOD1) gene account for approximately 20% of familial ALS and 2% of all ALS cases. Although a number of hypotheses have been proposed to explain mutant SOD1 toxicity...

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Detalles Bibliográficos
Autores principales: Kumimoto, Emily L., Fore, Taylor R., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618356/
https://www.ncbi.nlm.nih.gov/pubmed/23550139
http://dx.doi.org/10.1534/g3.113.005850