TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells

TRIM16 exhibits tumour suppressor functions by interacting with cytoplasmic vimentin and nuclear E2F1 proteins in neuroblastoma and squamous cell carcinoma cells, reducing cell migration and replication. Reduced TRIM16 expression in a range of human primary malignant tissues correlates with increase...

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Detalles Bibliográficos
Autores principales: Kim, Patrick Y., Rahmanto, Aldwin Suryo, Tan, Owen, Norris, Murray D., Haber, Michelle, Marshall, Glenn M., Cheung, Belamy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618413/
https://www.ncbi.nlm.nih.gov/pubmed/23404198
http://dx.doi.org/10.1007/s10495-013-0813-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618413/
https://www.ncbi.nlm.nih.gov/pubmed/23404198
http://dx.doi.org/10.1007/s10495-013-0813-y

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