A pseudogene long noncoding RNA network regulates PTEN transcription and translation in human cells

PTEN is a tumor suppressor gene that has been shown to be under the regulatory control of a PTEN pseudogene expressed noncoding RNA, PTENpg1. Here, we characterize a previously unidentified PTENpg1 encoded antisense RNA (asRNA), which regulates PTEN transcription and PTEN mRNA stability. We find two...

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Detalles Bibliográficos
Autores principales: Johnsson, Per, Ackley, Amanda, Vidarsdottir, Linda, Lui, Weng-Onn, Corcoran, Martin, Grandér, Dan, Morris, Kevin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618526/
https://www.ncbi.nlm.nih.gov/pubmed/23435381
http://dx.doi.org/10.1038/nsmb.2516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618526/
https://www.ncbi.nlm.nih.gov/pubmed/23435381
http://dx.doi.org/10.1038/nsmb.2516

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