Crystal Structure of Oligomeric β(1)-Adrenergic G Protein- Coupled Receptors in Ligand-Free Basal State

G protein-coupled receptors (GPCRs) mediate transmembrane signaling. Before ligand binding, GPCRs exist in a basal state. Crystal structures of several GPCRs bound with antagonists or agonists have been solved. However, the crystal structure of the ligand-free basal state of a GPCR, the starting poi...

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Detalles Bibliográficos
Autores principales: Huang, Jianyun, Chen, Shuai, Zhang, J. Jillian, Huang, Xin-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618578/
https://www.ncbi.nlm.nih.gov/pubmed/23435379
http://dx.doi.org/10.1038/nsmb.2504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618578/
https://www.ncbi.nlm.nih.gov/pubmed/23435379
http://dx.doi.org/10.1038/nsmb.2504

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