Cargando…
Crystal Structure of Oligomeric β(1)-Adrenergic G Protein- Coupled Receptors in Ligand-Free Basal State
G protein-coupled receptors (GPCRs) mediate transmembrane signaling. Before ligand binding, GPCRs exist in a basal state. Crystal structures of several GPCRs bound with antagonists or agonists have been solved. However, the crystal structure of the ligand-free basal state of a GPCR, the starting poi...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618578/ https://www.ncbi.nlm.nih.gov/pubmed/23435379 http://dx.doi.org/10.1038/nsmb.2504 |