From BACE1 Inhibitor to Multifunctionality of Tryptoline and Tryptamine Triazole Derivatives for Alzheimer’s Disease

Efforts to discover new drugs for Alzheimer’s disease emphasizing multiple targets was conducted seeking to inhibit amyloid oligomer formation and to prevent radical formation. The tryptoline and tryptamine cores of BACE1 inhibitors previously identified by virtual screening were modified in silico...

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Detalles Bibliográficos
Autores principales: Jiaranaikulwanitch, Jutamas, Govitrapong, Piyarat, Fokin, Valery V., Vajragupta, Opa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618987/
https://www.ncbi.nlm.nih.gov/pubmed/22781443
http://dx.doi.org/10.3390/molecules17078312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618987/
https://www.ncbi.nlm.nih.gov/pubmed/22781443
http://dx.doi.org/10.3390/molecules17078312

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