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A randomised double-blind placebo-controlled phase II study of AGI004 for control of chemotherapy-induced diarrhoea

BACKGROUND: AGI004 is a controlled-release transdermal patch preparation of mecamylamine. We conducted a randomised placebo-controlled phase II study of two dose levels of AGI004 in chemotherapy-induced diarrhoea (CID). METHODS: Adult patients receiving chemotherapy who had experienced diarrhoea (NC...

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Detalles Bibliográficos
Autores principales: Coyle, V M, Lungulescu, D, Toganel, C, Niculescu, A, Pop, S, Ciuleanu, T, Cebotaru, C, Devane, J, Martin, M, Wilson, R H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619064/
https://www.ncbi.nlm.nih.gov/pubmed/23462724
http://dx.doi.org/10.1038/bjc.2013.35