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Whole-genome methylation analysis of benign and malignant colorectal tumours

Changes in DNA methylation, whether hypo- or hypermethylation, have been shown to be associated with the progression of colorectal cancer. Methylation changes substantially in the progression from normal mucosa to adenoma and to carcinoma. This phenomenon has not been studied extensively and studies...

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Detalles Bibliográficos
Autores principales: Beggs, Andrew D, Jones, Angela, El-Bahwary, Mona, Abulafi, Muti, Hodgson, Shirley V, Tomlinson, Ian PM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619233/
https://www.ncbi.nlm.nih.gov/pubmed/23096130
http://dx.doi.org/10.1002/path.4132