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IF(1) limits the apoptotic-signalling cascade by preventing mitochondrial remodelling
Mitochondrial structure has a central role both in energy conversion and in the regulation of cell death. We have previously shown that IF(1) protects cells from necrotic cell death and supports cristae structure by promoting the oligomerisation of the F(1)F(o)-ATPsynthase. As IF(1) is upregulated i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619234/ https://www.ncbi.nlm.nih.gov/pubmed/23348567 http://dx.doi.org/10.1038/cdd.2012.163 |