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IF(1) limits the apoptotic-signalling cascade by preventing mitochondrial remodelling

Mitochondrial structure has a central role both in energy conversion and in the regulation of cell death. We have previously shown that IF(1) protects cells from necrotic cell death and supports cristae structure by promoting the oligomerisation of the F(1)F(o)-ATPsynthase. As IF(1) is upregulated i...

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Detalles Bibliográficos
Autores principales:	Faccenda, D, Tan, C H, Seraphim, A, Duchen, M R, Campanella, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619234/ https://www.ncbi.nlm.nih.gov/pubmed/23348567 http://dx.doi.org/10.1038/cdd.2012.163

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