Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer

BACKGROUND: Necdin (NDN) expression is downregulated in telomerase-immortalised normal human urothelial cells. Telomerase-immortalised normal human urothelial cells have no detected genetic alterations. Accordingly, many of the genes whose expression is altered following immortalisation are those fo...

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Detalles Bibliográficos
Autores principales: De Faveri, L E, Hurst, C D, Platt, F M, Taylor, C F, Roulson, J-A, Sanchez-Carbayo, M, Knowles, M A, Chapman, E J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics & Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619261/
https://www.ncbi.nlm.nih.gov/pubmed/23549060
http://dx.doi.org/10.1038/bjc.2013.104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619261/
https://www.ncbi.nlm.nih.gov/pubmed/23549060
http://dx.doi.org/10.1038/bjc.2013.104

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