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A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria

The dominant paradigm for the evolution of mutator alleles in bacterial populations is that they spread by indirect selection for linked beneficial mutations when bacteria are poorly adapted. In this paper, we challenge the ubiquity of this paradigm by demonstrating that a clinically important stres...

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Detalles Bibliográficos
Autores principales: Torres-Barceló, Clara, Cabot, Gabriel, Oliver, Antonio, Buckling, Angus, MacLean, R. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619485/
https://www.ncbi.nlm.nih.gov/pubmed/23446530
http://dx.doi.org/10.1098/rspb.2013.0007