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Human melanopsin forms a pigment maximally sensitive to blue light (λ(max) ≈ 479 nm) supporting activation of G(q)(/11) and G(i/o) signalling cascades
A subset of mammalian retinal ganglion cells expresses an opsin photopigment (melanopsin, Opn4) and is intrinsically photosensitive. The human retina contains melanopsin, but the literature lacks a direct investigation of its spectral sensitivity or G-protein selectivity. Here, we address this defic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619500/ https://www.ncbi.nlm.nih.gov/pubmed/23554393 http://dx.doi.org/10.1098/rspb.2012.2987 |