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Human melanopsin forms a pigment maximally sensitive to blue light (λ(max) ≈ 479 nm) supporting activation of G(q)(/11) and G(i/o) signalling cascades

A subset of mammalian retinal ganglion cells expresses an opsin photopigment (melanopsin, Opn4) and is intrinsically photosensitive. The human retina contains melanopsin, but the literature lacks a direct investigation of its spectral sensitivity or G-protein selectivity. Here, we address this defic...

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Detalles Bibliográficos
Autores principales: Bailes, Helena J., Lucas, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619500/
https://www.ncbi.nlm.nih.gov/pubmed/23554393
http://dx.doi.org/10.1098/rspb.2012.2987