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Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation

Basophils and eosinophils play important roles in various host defense mechanisms but also act as harmful effectors in allergic disorders. We generated novel basophil- and eosinophil-depletion mouse models by introducing the human diphtheria toxin (DT) receptor gene under the control of the mouse CD...

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Detalles Bibliográficos
Autores principales: Matsuoka, Kunie, Shitara, Hiroshi, Taya, Choji, Kohno, Kenji, Kikkawa, Yoshiaki, Yonekawa, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620047/
https://www.ncbi.nlm.nih.gov/pubmed/23577180
http://dx.doi.org/10.1371/journal.pone.0060958