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Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation
Basophils and eosinophils play important roles in various host defense mechanisms but also act as harmful effectors in allergic disorders. We generated novel basophil- and eosinophil-depletion mouse models by introducing the human diphtheria toxin (DT) receptor gene under the control of the mouse CD...
Autores principales: | Matsuoka, Kunie, Shitara, Hiroshi, Taya, Choji, Kohno, Kenji, Kikkawa, Yoshiaki, Yonekawa, Hiromichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620047/ https://www.ncbi.nlm.nih.gov/pubmed/23577180 http://dx.doi.org/10.1371/journal.pone.0060958 |
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