Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

Microglial cells closely interact with senile plaques in Alzheimer’s disease and acquire the morphological appearance of an activated phenotype. The significance of this microglial phenotype and the impact of microglia for disease progression have remained controversial. To uncover and characterize...

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Detalles Bibliográficos
Autores principales: Krabbe, Grietje, Halle, Annett, Matyash, Vitali, Rinnenthal, Jan L., Eom, Gina D., Bernhardt, Ulrike, Miller, Kelly R., Prokop, Stefan, Kettenmann, Helmut, Heppner, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620049/
https://www.ncbi.nlm.nih.gov/pubmed/23577177
http://dx.doi.org/10.1371/journal.pone.0060921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620049/
https://www.ncbi.nlm.nih.gov/pubmed/23577177
http://dx.doi.org/10.1371/journal.pone.0060921

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