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Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
Microglial cells closely interact with senile plaques in Alzheimer’s disease and acquire the morphological appearance of an activated phenotype. The significance of this microglial phenotype and the impact of microglia for disease progression have remained controversial. To uncover and characterize...
Autores principales: | Krabbe, Grietje, Halle, Annett, Matyash, Vitali, Rinnenthal, Jan L., Eom, Gina D., Bernhardt, Ulrike, Miller, Kelly R., Prokop, Stefan, Kettenmann, Helmut, Heppner, Frank L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620049/ https://www.ncbi.nlm.nih.gov/pubmed/23577177 http://dx.doi.org/10.1371/journal.pone.0060921 |
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