Overexpression of Full-Length Centrobin Rescues Limb Malformation but Not Male Fertility of the Hypodactylous (hd) Rats

Rat hypodactyly (hd) mutation is characterized by abnormal spermatogenesis and sperm decapitation, limb malformation (missing digits II and III) and growth retardation. We have previously reported centrobin (centrosome BRCA2-interacting protein) truncation at the C-terminus in the hd mutant. Here, w...

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Detalles Bibliográficos
Autores principales: Liška, František, Gosele, Claudia, Popova, Elena, Chylíková, Blanka, Křenová, Drahomíra, Křen, Vladimír, Bader, Michael, Tres, Laura L., Hubner, Norbert, Kierszenbaum, Abraham L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620055/
https://www.ncbi.nlm.nih.gov/pubmed/23577170
http://dx.doi.org/10.1371/journal.pone.0060859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620055/
https://www.ncbi.nlm.nih.gov/pubmed/23577170
http://dx.doi.org/10.1371/journal.pone.0060859

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