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PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study

INTRODUCTION: Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease influenced by both genetic and environmental factors, leading to joint destruction and functional impairment. Recently, a large-scaled GWAS meta-analysis using more than 37,000 Japanese samples were conducted and 13...

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Detalles Bibliográficos
Autores principales: Suzuki, Taku, Ikari, Katsunori, Yano, Koichiro, Inoue, Eisuke, Toyama, Yoshiaki, Taniguchi, Atsuo, Yamanaka, Hisashi, Momohara, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620057/
https://www.ncbi.nlm.nih.gov/pubmed/23577190
http://dx.doi.org/10.1371/journal.pone.0061045