Cargando…

PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study

INTRODUCTION: Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease influenced by both genetic and environmental factors, leading to joint destruction and functional impairment. Recently, a large-scaled GWAS meta-analysis using more than 37,000 Japanese samples were conducted and 13...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suzuki, Taku, Ikari, Katsunori, Yano, Koichiro, Inoue, Eisuke, Toyama, Yoshiaki, Taniguchi, Atsuo, Yamanaka, Hisashi, Momohara, Shigeki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620057/ https://www.ncbi.nlm.nih.gov/pubmed/23577190 http://dx.doi.org/10.1371/journal.pone.0061045

Ejemplares similares

An Osteoprotegerin Gene Polymorphism Is Associated with an Increased Risk of Hip Fracture in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Observational Cohort Study
por: Yoshida, Shinji, et al.
Publicado: (2014)

Response to ‘Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study’
por: Ikari, Katsunori, et al.
Publicado: (2014)

Studies of the efficacy and safety of methotrexate at dosages over 8 mg/week using the IORRA cohort database
por: Seto, Yohei, et al.
Publicado: (2011)

Features of patients with rheumatoid arthritis whose debut joint is a foot or ankle joint: A 5,479-case study from the IORRA cohort
por: Yano, Koichiro, et al.
Publicado: (2018)

A GC polymorphism associated with serum 25-hydroxyvitamin D level is a risk factor for hip fracture in Japanese patients with rheumatoid arthritis: 10-year follow-up of the Institute of Rheumatology, Rheumatoid Arthritis cohort study
por: Yoshida, Shinji, et al.
Publicado: (2014)

ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese
por: Terao, Chikashi, et al.
Publicado: (2012)

Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population
por: Terao, Chikashi, et al.
Publicado: (2015)

Cost-consequence of abatacept as first-line therapy in Japanese rheumatoid arthritis patients using IORRA real-world data
por: Tanaka, Eiichi, et al.
Publicado: (2022)

PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis
por: Hisa, Kaori, et al.
Publicado: (2017)

Time-averaged disease activity fits better joint destruction in rheumatoid arthritis
por: Tsuji, Hideaki, et al.
Publicado: (2017)

The lack of association between PADI4_94 or PADI4_104 polymorphisms and RF, ACPA and anti-PAD4 in patients with rheumatoid arthritis
por: Ciesla, Marek, et al.
Publicado: (2022)

Ways forward to identify new ACPA targets in RA
por: Ytterberg, A Jimmy, et al.
Publicado: (2012)

ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population
por: Iikuni, Noriko, et al.
Publicado: (2007)

Anti-centromere antibody exhibits specific distribution levels among anti-nuclear antibodies and may characterize a distinct subset in rheumatoid arthritis
por: Kuramoto, Nobuo, et al.
Publicado: (2017)

HLA-DRB1 Genotypes and the Risk of Developing Anti Citrullinated Protein Antibody (ACPA) Positive Rheumatoid Arthritis
por: Balandraud, Nathalie, et al.
Publicado: (2013)

ACPA-negative and ACPA-positive RA patients achieving disease resolution demonstrate distinct patterns of MRI-detected joint-inflammation
por: Verstappen, Marloes, et al.
Publicado: (2022)

In Rheumatoid Arthritis Patients, HLA-DRB1*04:01 and Rheumatoid Nodules Are Associated With ACPA to a Particular Fibrin Epitope
por: Larid, Guillaume, et al.
Publicado: (2021)

PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking
por: Massarenti, Laura, et al.
Publicado: (2021)

Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese
por: Myouzen, Keiko, et al.
Publicado: (2012)

Factors associated with osteoporosis medication use in Japanese patients with rheumatoid arthritis: Results from the Institute of Rheumatology Rheumatoid Arthritis cohort study
por: Nakayama, Masanori, et al.
Publicado: (2020)

Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients
por: Xu, Minjie, et al.
Publicado: (2023)

Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line
por: Imamura, Hitoshi, et al.
Publicado: (2016)

Outcomes of Joint-Preserving Surgery for Rheumatoid Forefoot Deformity: An Editorial
por: Yano, Koichiro, et al.
Publicado: (2022)

PADI4 Haplotypes in Association with RA Mexican Patients, a New Prospect for Antigen Modulation
por: Zavala-Cerna, Maria Guadalupe, et al.
Publicado: (2013)

HLA-DRB1*07:01 and *08:02 Alleles Confer a Protective Effect Against ACPA-Positive Rheumatoid Arthritis in a Latin American Admixed Population
por: Castro-Santos, Patricia, et al.
Publicado: (2020)

Influence of HLA-DRB1 P4 binding pocket electric charge on rheumatoid arthritis (RA) susceptibility
por: Michou, L, et al.
Publicado: (2003)

Response to the ACPA's critique.
por: Repetto, R, et al.
Publicado: (1998)

Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione s-transferase in a cross-sectional study
por: Mikuls, Ted R, et al.
Publicado: (2010)

Differing time-orders of inflammation decrease between ACPA subsets in RA patients suggest differences in underlying inflammatory pathways
por: Matthijssen, Xanthe M E, et al.
Publicado: (2020)

Autoantikörper und die autoreaktive Immunantwort: ACPA sind mehr als nur ACPA
por: Scherer, H. U.
Publicado: (2020)

PADI4 and tumourigenesis
por: Chang, Xiaotian, et al.
Publicado: (2010)

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF
por: Boeters, Debbie M., et al.
Publicado: (2016)

Effect of an orthosis on foot center of pressure translation for treatment of hallux valgus in patients with rheumatoid arthritis: A report of 17 cases
por: Mochizuki, Takeshi, et al.
Publicado: (2019)

Comparison of patient-reported outcomes of treatment with low- and intermediate molecular weight hyaluronic acid in Japanese patients with symptomatic knee osteoarthritis: A prospective, randomized, single-blind trial
por: Mochizuki, Takeshi, et al.
Publicado: (2020)

Safety and Efficacy of Zoledronic Acid Treatment with and without Acetaminophen and Eldecalcitol for Osteoporosis
por: Mochizuki, Takeshi, et al.
Publicado: (2021)

Effects of romosozumab or denosumab treatment on the bone mineral density and disease activity for 6 months in patients with rheumatoid arthritis with severe osteoporosis: An open-label, randomized, pilot study
por: Mochizuki, Takeshi, et al.
Publicado: (2021)

Two-year effectiveness of zoledronic acid with or without eldecalcitol in Japanese patients with osteoporosis: A randomized prospective study
por: Mochizuki, Takeshi, et al.
Publicado: (2022)

Factors Associated with Five-year Deterioration of the Health Assessment Questionnaire-Disability Index in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study
por: Mochizuki, Takeshi, et al.
Publicado: (2022)

CCR6(+) Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis
por: Paulissen, Sandra M. J., et al.
Publicado: (2015)

A Replication Study Confirms the Association of Dendritic Cell Immunoreceptor (DCIR) Polymorphisms with ACPA - Negative RA in a Large Asian Cohort
por: Guo, Jianping, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_c30oo0uspb85b6ur2uaeouua0e