Reduced Androgen Receptor Expression Accelerates the Onset of ERBB2 Induced Breast Tumors in Female Mice

Androgen receptor (AR) is commonly expressed in both the epithelium of normal mammary glands and in breast cancers. AR expression in breast cancers is independent of estrogen receptor alpha (ERα) status and is frequently associated with overexpression of the ERBB2 oncogene. AR signaling effects on b...

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Detalles Bibliográficos
Autores principales: Hodgson, Myles C., VanOstran, Garrett, Alghamdi, Sarah, Poppiti, Robert J., Agoulnik, Alexander I., Agoulnik, Irina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620158/
https://www.ncbi.nlm.nih.gov/pubmed/23593223
http://dx.doi.org/10.1371/journal.pone.0060455