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A Pilot Study of the Effect of Sodium Thiosulfate on Urinary Lithogenicity and Associated Metabolic Acid Load in Non-Stone Formers and Stone Formers with Hypercalciuria

BACKGROUND AND OBJECTIVES: Sodium thiosulfate (STS) reduced calcium stone formation in both humans and genetic hypercalciuric stone forming (GHS) rats. We sought to measure urine chemistry changes resulting from STS administration in people. DESIGN, SETTING, PARTICIPANTS & MEASUREMENTS: STS was...

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Detalles Bibliográficos
Autores principales: Okonkwo, Onyeka W., Batwara, Ruchika, Granja, Ignacio, Asplin, John R., Goldfarb, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620159/
https://www.ncbi.nlm.nih.gov/pubmed/23593205
http://dx.doi.org/10.1371/journal.pone.0060380