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Amikacin-induced Fin Reduction is Mediated by Autophagy

Despite its medical use, little is known about the mechanisms underlying amikacin-induced embryotoxicity, including fin reduction, in zebrafish. In this study, we examined the expression of well-known autophagy markers mTOR (target of rapamycin), atg10 (autophagy-related gene), atg12 and LC3 (mammal...

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Detalles Bibliográficos
Autores principales: Tsai, I-Ting, Chen, Ying-Hsin, Chen, Yau-Hung, Wang, Yun-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620219/
https://www.ncbi.nlm.nih.gov/pubmed/23723573
http://dx.doi.org/10.1293/tox.26.79