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Protective Role of Acidic pH-Activated Chloride Channel in Severe Acidosis-Induced Contraction from the Aorta of Spontaneously Hypertensive Rats

Severe acidic pH-activated chloride channel (I(Cl,acid)) has been found in various mammalian cells. In the present study, we investigate whether this channel participates in reactions of the thoracic aorta to severe acidosis and whether it plays a role in hypertension. We measured isometric contract...

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Detalles Bibliográficos
Autores principales: Ma, Zhiyong, Qi, Jia, Fu, Zhijie, Ling, Mingying, Li, Li, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620281/
https://www.ncbi.nlm.nih.gov/pubmed/23580361
http://dx.doi.org/10.1371/journal.pone.0061018