Optimisation of Embryonic and Larval ECG Measurement in Zebrafish for Quantifying the Effect of QT Prolonging Drugs

Effective chemical compound toxicity screening is of paramount importance for safe cardiac drug development. Using mammals in preliminary screening for detection of cardiac dysfunction by electrocardiography (ECG) is costly and requires a large number of animals. Alternatively, zebrafish embryos can...

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Detalles Bibliográficos
Autores principales: Dhillon, Sundeep Singh, Dóró, Éva, Magyary, István, Egginton, Stuart, Sík, Attila, Müller, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620317/
https://www.ncbi.nlm.nih.gov/pubmed/23579446
http://dx.doi.org/10.1371/journal.pone.0060552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620317/
https://www.ncbi.nlm.nih.gov/pubmed/23579446
http://dx.doi.org/10.1371/journal.pone.0060552

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