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An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes
BACKGROUND: Cancer cells typically exhibit large-scale aberrant methylation of gene promoters. Some of the genes with promoter methylation alterations play “driver” roles in tumorigenesis, whereas others are only “passengers”. RESULTS: Based on the assumption that promoter methylation alteration of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620319/ https://www.ncbi.nlm.nih.gov/pubmed/23579546 http://dx.doi.org/10.1371/journal.pone.0061214 |