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Bovine Lactoferrin Decreases Cholera-Toxin-Induced Intestinal Fluid Accumulation in Mice by Ganglioside Interaction

Secretory diarrhea caused by cholera toxin (CT) is initiated by binding of CT’s B subunit (CTB) to GM1-ganglioside on the surface of intestinal cells. Lactoferrin, a breast milk glycoprotein, has shown protective effect against several enteropathogens. The aims of this study were to determine the ef...

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Detalles Bibliográficos
Autores principales: Rivera, Fulton P., Medina, Anicia M., Bezada, Sandra, Valencia, Roberto, Bernal, María, Meza, Rina, Maves, Ryan C., Ochoa, Theresa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620325/
https://www.ncbi.nlm.nih.gov/pubmed/23580005
http://dx.doi.org/10.1371/journal.pone.0059253