Loss of β-Glucocerebrosidase Activity Does Not Affect Alpha-Synuclein Levels or Lysosomal Function in Neuronal Cells

To date, a plethora of studies have provided evidence favoring an association between Gaucher disease (GD) and Parkinson’s disease (PD). GD, the most common lysosomal storage disorder, results from the diminished activity of the lysosomal enzyme β-glucocerebrosidase (GCase), caused by mutations in t...

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Detalles Bibliográficos
Autores principales: Dermentzaki, Georgia, Dimitriou, Evangelia, Xilouri, Maria, Michelakakis, Helen, Stefanis, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620326/
https://www.ncbi.nlm.nih.gov/pubmed/23580063
http://dx.doi.org/10.1371/journal.pone.0060674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620326/
https://www.ncbi.nlm.nih.gov/pubmed/23580063
http://dx.doi.org/10.1371/journal.pone.0060674

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