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Prion Protein Gene Variability in Spanish Goats. Inference through Susceptibility to Classical Scrapie Strains and Pathogenic Distribution of Peripheral PrP(sc)

Classical scrapie is a neurological disorder of the central nervous system (CNS) characterized by the accumulation of an abnormal, partially protease resistant prion protein (PrP(sc)) in the CNS and in some peripheral tissues in domestic small ruminants. Whereas the pathological changes and genetic...

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Detalles Bibliográficos
Autores principales: Acín, Cristina, Martín-Burriel, Inmaculada, Monleón, Eva, Lyahyai, Jaber, Pitarch, José Luis, Serrano, Carmen, Monzón, Marta, Zaragoza, Pilar, Badiola, Juan José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620333/
https://www.ncbi.nlm.nih.gov/pubmed/23580248
http://dx.doi.org/10.1371/journal.pone.0061118