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Expression of p15(INK4b) and p57(KIP2) and Relationship with Clinicopathological Features and Prognosis in Patients with Vulvar Squamous Cell Carcinoma

BACKGROUND: The cyclin-dependent kinase inhibitors p15(INK4b) and p57(KIP2) are important regulators of the cell cycle, and their abnormal expression has been detected in various tumors. However, little is known about the role of p15(INK4b) and p57(KIP2) in the pathogenesis of vulvar carcinoma, and...

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Detalles Bibliográficos
Autores principales: Holm, Ruth, Førsund, Mette, Nguyen, Mai T., Nesland, Jahn M., Trope, Claes G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620337/
https://www.ncbi.nlm.nih.gov/pubmed/23580324
http://dx.doi.org/10.1371/journal.pone.0061273