PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

Immune responses to persistent viral infections and cancer often fail because of intense regulation of antigen-specific T cells—a process referred to as immune exhaustion. The mechanisms that underlie the induction of exhaustion are not completely understood. To gain novel insights into this process...

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Detalles Bibliográficos
Autores principales: Zinselmeyer, Bernd H., Heydari, Sara, Sacristán, Catarina, Nayak, Debasis, Cammer, Michael, Herz, Jasmin, Cheng, Xiaoxiao, Davis, Simon J., Dustin, Michael L., McGavern, Dorian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620347/
https://www.ncbi.nlm.nih.gov/pubmed/23530125
http://dx.doi.org/10.1084/jem.20121416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620347/
https://www.ncbi.nlm.nih.gov/pubmed/23530125
http://dx.doi.org/10.1084/jem.20121416

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