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Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin
4-1BB agonist antibody treatment induces a population of KLRG1(+) T cells that infiltrate melanoma tumors. We investigated the origin and function of these cells, as well as their place within established T cell paradigms. We find that these T cells, particularly the CD4 lineage, represent a novel p...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620352/ https://www.ncbi.nlm.nih.gov/pubmed/23547098 http://dx.doi.org/10.1084/jem.20121190 |