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CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens

CD1c is expressed with high density on human dendritic cells (DCs) and B cells, yet its antigen presentation functions are the least well understood among CD1 family members. Using a CD1c-reactive T cell line (DN6) to complete an organism-wide survey of M. tuberculosis lipids, we identified C32 phos...

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Detalles Bibliográficos
Autores principales: Ly, Dalam, Kasmar, Anne G., Cheng, Tan-Yun, de Jong, Annemieke, Huang, Shouxiong, Roy, Sobhan, Bhatt, Apoorva, van Summeren, Ruben P., Altman, John D., Jacobs, William R., Adams, Erin J., Minnaard, Adriaan J., Porcelli, Steven A., Moody, D. Branch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620358/
https://www.ncbi.nlm.nih.gov/pubmed/23530121
http://dx.doi.org/10.1084/jem.20120624