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Lung-resident tissue macrophages generate Foxp3(+) regulatory T cells and promote airway tolerance
Airway tolerance is the usual outcome of inhalation of harmless antigens. Although T cell deletion and anergy are likely components of tolerogenic mechanisms in the lung, increasing evidence indicates that antigen-specific regulatory T cells (inducible T(reg) cells [iT(reg) cells]) that express Foxp...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620360/ https://www.ncbi.nlm.nih.gov/pubmed/23547101 http://dx.doi.org/10.1084/jem.20121849 |