Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice

Dehydroepiandrosterone (DHEA) is the most abundant neurosteroid synthesized de novo in the central nervous system. We previously reported that stimulation of the sigma-1 receptor by DHEA improves cognitive function by activating calcium/calmodulin-dependent protein kinase II (CaMKII), protein kinase...

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Detalles Bibliográficos
Autores principales: Moriguchi, Shigeki, Shinoda, Yasuharu, Yamamoto, Yui, Sasaki, Yuzuru, Miyajima, Kosuke, Tagashira, Hideaki, Fukunaga, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620380/
https://www.ncbi.nlm.nih.gov/pubmed/23593332
http://dx.doi.org/10.1371/journal.pone.0060863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620380/
https://www.ncbi.nlm.nih.gov/pubmed/23593332
http://dx.doi.org/10.1371/journal.pone.0060863

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