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Targeting the EGFR/PCNA Signaling Suppresses Tumor Growth of Triple-Negative Breast Cancer Cells with Cell-Penetrating PCNA Peptides

Tyrosine 211 (Y211) phosphorylation of proliferation cell nuclear antigen (PCNA) coincides with pronounced cancer cell proliferation and correlates with poor survival of breast cancer patients. In epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-resistant cells, both nuclear E...

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Detalles Bibliográficos
Autores principales: Yu, Yung-Luen, Chou, Ruey-Hwang, Liang, Jia-Hong, Chang, Wei-Jung, Su, Kuo-Jung, Tseng, Yen-Ju, Huang, Wei-Chien, Wang, Shao-Chun, Hung, Mien-Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620387/
https://www.ncbi.nlm.nih.gov/pubmed/23593472
http://dx.doi.org/10.1371/journal.pone.0061362