Functional Deficits in Pak5, Pak6 and Pak5/Pak6 Knockout Mice

The p21-activated kinases are effector proteins for Rho-family GTPases. PAK4, PAK5, and PAK6 are the group II PAKs associated with neurite outgrowth, filopodia formation, and cell survival. Pak4 knockout mice are embryonic lethal, while Pak5, Pak6, and Pak5/Pak6 double knockout mice are viable and f...

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Detalles Bibliográficos
Autores principales: Furnari, Melody A., Jobes, Michelle L., Nekrasova, Tanya, Minden, Audrey, Wagner, George C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620390/
https://www.ncbi.nlm.nih.gov/pubmed/23593460
http://dx.doi.org/10.1371/journal.pone.0061321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620390/
https://www.ncbi.nlm.nih.gov/pubmed/23593460
http://dx.doi.org/10.1371/journal.pone.0061321

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