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Mutual Antagonism between Circadian Protein Period 2 and Hepatitis C Virus Replication in Hepatocytes
BACKGROUND: Hepatitis C virus (HCV) infects approximately 3% of the world population and is the leading cause of liver disease, impacting hepatocyte metabolism, depending on virus genotype. Hepatic metabolic functions show rhythmic fluctuations with 24-h periodicity (circadian), driven by molecular...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620463/ https://www.ncbi.nlm.nih.gov/pubmed/23593233 http://dx.doi.org/10.1371/journal.pone.0060527 |