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Willin, an Upstream Component of the Hippo Signaling Pathway, Orchestrates Mammalian Peripheral Nerve Fibroblasts
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional co-activator YAP through Ser127 phosphorylation. This in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620498/ https://www.ncbi.nlm.nih.gov/pubmed/23593160 http://dx.doi.org/10.1371/journal.pone.0060028 |