Willin, an Upstream Component of the Hippo Signaling Pathway, Orchestrates Mammalian Peripheral Nerve Fibroblasts

Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional co-activator YAP through Ser127 phosphorylation. This in...

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Detalles Bibliográficos
Autores principales: Moleirinho, Susana, Patrick, Calum, Tilston-Lünel, Andrew M., Higginson, Jennifer R., Angus, Liselotte, Antkowiak, Maciej, Barnett, Susan C., Prystowsky, Michael B., Reynolds, Paul A., Gunn-Moore, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620498/
https://www.ncbi.nlm.nih.gov/pubmed/23593160
http://dx.doi.org/10.1371/journal.pone.0060028

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