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Epigenetic modification of the Epstein-Barr virus BZLF1 promoter regulates viral reactivation from latency

The Epstein–Barr virus (EBV) is an oncogenic human gamma-herpesvirus that predominantly establishes latent infection in B lymphocytes. Viral genomes exist as extrachromosomal episomes with a nucleosomal structure. Maintenance of virus latency or execution of reactivation is controlled by the express...

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Detalles Bibliográficos
Autores principales: Murata, Takayuki, Tsurumi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620531/
https://www.ncbi.nlm.nih.gov/pubmed/23577022
http://dx.doi.org/10.3389/fgene.2013.00053