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Epigenetic modification of the Epstein-Barr virus BZLF1 promoter regulates viral reactivation from latency
The Epstein–Barr virus (EBV) is an oncogenic human gamma-herpesvirus that predominantly establishes latent infection in B lymphocytes. Viral genomes exist as extrachromosomal episomes with a nucleosomal structure. Maintenance of virus latency or execution of reactivation is controlled by the express...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620531/ https://www.ncbi.nlm.nih.gov/pubmed/23577022 http://dx.doi.org/10.3389/fgene.2013.00053 |