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Quantitative Peptidomics of Purkinje Cell Degeneration Mice

Cytosolic carboxypeptidase 1 (CCP1) is a metallopeptidase that removes C-terminal and side-chain glutamates from tubulin. The Purkinje cell degeneration (pcd) mouse lacks CCP1 due to a mutation. Previously, elevated levels of peptides derived from cytosolic and mitochondrial proteins were found in a...

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Detalles Bibliográficos
Autores principales: Berezniuk, Iryna, Sironi, Juan J., Wardman, Jonathan, Pasek, Raymond C., Berbari, Nicolas F., Yoder, Bradley K., Fricker, Lloyd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620535/
https://www.ncbi.nlm.nih.gov/pubmed/23593366
http://dx.doi.org/10.1371/journal.pone.0060981